Treatment of medically intractable partial seizures with responsive stimulation
نویسندگان
چکیده
Ashwini Sharan MD , Charles Liu MD PhD, Cole Giller MD, Daniel Yoshor MD, David Roberts MD, Emad Eskandar MD, James Evans MD, Jason Schwalb MD, John Ragheb MD, Karl Sillay MD, Peter Weber MD, Richard Byrne MD, Richard Marsh MD, Richard Zimmernan MD, Robert Goodman MD PhD, Robert Wharen MD, Robert Worth MD PhD, Steven Glazier MD, Thomas Witt MD, Tony Whitworth MD, Werner Doyle MD, William Bingaman MD (Disclosure for all listed above: University Grant/Research Support – NeuroPace, Inc.) Martha Morrell MD (Disclosure: Employee: NeuroPace, Inc.)
منابع مشابه
Responsive cortical stimulation for the treatment of medically intractable partial epilepsy.
OBJECTIVES This multicenter, double-blind, randomized controlled trial assessed the safety and effectiveness of responsive cortical stimulation as an adjunctive therapy for partial onset seizures in adults with medically refractory epilepsy. METHODS A total of 191 adults with medically intractable partial epilepsy were implanted with a responsive neurostimulator connected to depth or subdural...
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OBJECTIVE To demonstrate the safety and effectiveness of responsive stimulation at the seizure focus as an adjunctive therapy to reduce the frequency of seizures in adults with medically intractable partial onset seizures arising from one or two seizure foci. METHODS Randomized multicenter double-blinded controlled trial of responsive focal cortical stimulation (RNS System). Subjects with med...
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OBJECTIVE Evaluate the seizure-reduction response and safety of brain-responsive stimulation in adults with medically intractable partial-onset seizures of neocortical origin. METHODS Patients with partial seizures of neocortical origin were identified from prospective clinical trials of a brain-responsive neurostimulator (RNS System, NeuroPace). The seizure reduction over years 2-6 postimpla...
متن کاملQuality of life and mood in patients with medically intractable epilepsy treated with targeted responsive neurostimulation
PURPOSE The primary efficacy and safety measures from a trial of responsive neurostimulation for focal epilepsy were previously published. In this report, the findings from the same study are presented for quality of life, which was a supportive analysis, and for mood, which was assessed as a secondary safety endpoint. METHODS The study was a multicenter randomized controlled double-blinded t...
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We evaluated the effect of low-frequency repetitive transcranial magnetic stimulation (rTMS) on seizure frequency in adult patients with medically intractable extratemporal lobe epilepsy (ETLE). Seven patients with medically intractable ETLE received low-frequency rTMS at 0.9 Hz, basically two sets of 15 min stimulation per day for five days in a week, with the stimulus intensity of 90% of rest...
متن کاملLong-term treatment with responsive brain stimulation in adults with refractory partial seizures
OBJECTIVE The long-term efficacy and safety of responsive direct neurostimulation was assessed in adults with medically refractory partial onset seizures. METHODS All participants were treated with a cranially implanted responsive neurostimulator that delivers stimulation to 1 or 2 seizure foci via chronically implanted electrodes when specific electrocorticographic patterns are detected (RNS...
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تاریخ انتشار 2012